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VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The encoded protein plays a

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VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The encoded protein plays aVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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Description

The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3

Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

2005 [PubMed 16199532])

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

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VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The encoded protein plays aVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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