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Fli-1 Polyclonal Antibody, 50ul Protein Modification Mammalian mitochondrial ribosomal protein L

SKU: 15745677792

4.9
USD162.00 USD199.00

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Fli-1 Polyclonal Antibody, 50ul Protein Modification Mammalian mitochondrial ribosomal protein LFLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA binding domain. FLI1 can undergo a t (11; 22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia associated t (4; 11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple

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Description

Mammalian mitochondrial ribosomal protein L 13 (39S ribosomal protein L13 mitochondrial) is encoded by nuclear gene MRPL13 and help in protein synthesis within the mitochondrion

The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix

unlike ubiquitin which targets proteins for degradation

similar to Vps4 protein in yeast

Interacts with KDM5A

Fli-1 Polyclonal Antibody, 50ul Protein Modification Mammalian mitochondrial ribosomal protein LFLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA binding domain. FLI1 can undergo a t (11; 22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia associated t (4; 11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple

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