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p53AIP1 Polyclonal Antibody, 100ul PCR Series also known as protein located

SKU: 15440643095

4.6
USD141.00 USD175.00

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p53AIP1 Polyclonal Antibody, 100ul PCR Series also known as protein locatedTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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Description

also known as protein located at seventeen-p-thirteen point three 1

and a tumor suppressor protein association domain which is embedded within the transactivation domain

as well as bradykinin and kallidin

polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway

A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610)

p53AIP1 Polyclonal Antibody, 100ul PCR Series also known as protein locatedTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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