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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging ABC proteins transport various molecules

SKU: 15355002296

4.3
PLN108.00 PLN145.00

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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging ABC proteins transport various moleculesJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

ABC proteins transport various molecules across extra-and intra-cellular membranes

The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins

Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds

HM74B is highly expressed in adipocytes

AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging ABC proteins transport various moleculesJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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