IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04672] Contamination Detection & Removal May be functionally important for
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IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04672] Contamination Detection & Removal May be functionally important forNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. NF kappa B inhibitor alpha interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. NF kappa B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic
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