SMAD7 Polyclonal Antibody, 50ul Peptide Library Down-regulates PDPK1 kinase activity by

Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues

It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface

THY1 may function as a tumor suppressor in nasopharyngeal carcinoma

and murine studies suggest a role in tumor-associated tissue remodeling

The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development

SMAD7 Polyclonal Antibody, 50ul Peptide Library Down-regulates PDPK1 kinase activity byThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding