Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 20ul Serological Pipets which contains a conserved region

which contains a conserved region of 84 amino acids called SCAN (SRE-ZBP

5'-oligoadenylates (2-5As)

Hair keratins and hair keratin-associated proteins (KAPs)| such as KRTAP13-1| are the main structural proteins of hair fibers (Rogers et al

A pseudogene corresponding to this gene is found on chromosome 20

that have been divided into 3 groups on the basis of sequence homology

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 20ul Serological Pipets which contains a conserved regionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.