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PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes This gene is involved in

SKU: 12334101533

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PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes This gene is involved inThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

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Description

This gene is involved in epidermal differentiation| and it is expressed at high levels in normal and psoriatic skin| but not in cultured keratinocytes or in any other tested cell types or tissues

This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases

a receptor for the laminins

and an N-terminal regulatory domain (Habc)

The protein encoded by SMO (smoothened

PAPP2 Polyclonal Antibody, 50ul Cell Culture Dishes This gene is involved inThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

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