DPOG1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in INPP5D are associated

Mutations in INPP5D are associated with defects and cancers of the immune system

May be a transcriptional repressor

followed by heart

This protein has been proposed to protect cells from p53-dependent senescence and apoptosis

May play a role in cell proliferation of NT2 embryonal carcinoma cells

DPOG1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in INPP5D are associatedMitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy