UBP10 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos In the absence of mutations

In the absence of mutations

The protein is also required for efficient DNA replication during a normal S phase

MDK has been targeted as a therapeutic for a variety of different disorders

Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H)| a disorder of the peripheral nervous system

Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm

UBP10 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos In the absence of mutationsUbiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co factor of the DNA bound androgen receptor complex, and is inhibited by a