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IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis Deficiency of this enzyme results

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IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis Deficiency of this enzyme resultsIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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Description

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

AASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway

and induces apoptosis in transfected cells

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize

IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis Deficiency of this enzyme resultsIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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